Guggul (Commiphora wightii)

Guggul is made from the sap (gum resin) of the Commiphora mukul tree, which is native to India. This tree has been used in Ayurvedic medicine for centuries, and Ayurvedic texts dating back to 600 BC recommend it for treating atherosclerosis.

Today guggul gum resin is used for arthritis, lowering high cholesterol, “hardening of the arteries” (atherosclerosis), acne and other skin diseases, and weight loss.

How does it work?

Guggul contains substances that lower cholesterol and triglycerides. One of these substances also decreases the redness and swelling that occurs in some types of acne.

Treating some types of acne.
High cholesterol.
Osteoarthritis.
Rheumatoid arthritis.

By Mouth:

For severe (nodulocystic) acne: a twice daily dose of guggul that contains up to 25 mg of the active ingredients called guggulsterones.

Guggul is SAFE for most people when taken by mouth appropriately. It has been used safely in clinical trials for up to 24 weeks. Some evidence also suggests that long-term use up to 75 weeks may be safe.

It can cause side effects such as stomach upset, headaches, nausea, vomiting, loose stools, diarrhea, belching, and hiccups. Guggul can also cause allergic reactions such as rash and itching. Guggul can also cause skin rash and itching that is not related to allergy. These adverse reactions are more common with higher doses, such as 6000 mg per day.

Pregnancy and breast-feeding: Guggul is LIKELY UNSAFE during pregnancy. It seems to encourage menstrual flow and stimulates the uterus, so some researchers worry that it might endanger the pregnancy. Not enough is known about the safety of using guggul during breast-feeding. Do not use guggul if you are pregnant or breast-feeding.

Bleeding disorders: Guggul can slow blood clotting and might cause bleeding or bruising in people with bleeding disorders.

Hormone-sensitive condition such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Guggul might act like estrogen in the body. If you have any condition that might be made worse by exposure to estrogen, do not use guggul.

Underactive or overactive thyroid (hypothyroidism or hyperthyroidism): Guggul might interfere with treatment for these conditions. If you have a thyroid condition, don't use guggul without your healthcare provider's supervision.

Surgery: Guggul might increase the risk of bleeding during and after surgery. Stop using guggul at least 2 weeks before a scheduled surgery.