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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


Iodine is a chemical element. The body needs iodine but cannot make it. The iodine needed by the body must come from the diet. As a rule, there is very little iodine in food, unless it has been added during processing. Processed food typically contains more iodine due to the addition of iodized salt. Most of the world's iodine is found in the ocean, where it is concentrated by sea life, especially seaweed.

The thyroid gland needs iodine to make hormones. If the thyroid doesn't have enough iodine to do its job, feedback systems in the body cause the thyroid to work harder. This can cause an enlarged thyroid gland (goiter), which becomes evident as a swollen neck.

Other consequences of not having enough iodine (iodine deficiency) are also serious. Iodine deficiency and the resulting low levels of thyroid hormone can cause women to stop ovulating, leading to infertility. Iodine deficiency can also lead to an autoimmune disease of the thyroid and may increase the risk of getting thyroid cancer. Some researchers think that iodine deficiency might also increase the risk of other cancers such as prostate, breast, endometrial, and ovarian cancer.

Iodine deficiency during pregnancy is serious for both the mother and the baby. It can lead to high blood pressure during pregnancy for the mother, and mental retardation for the baby. Iodine plays an important role in development of the central nervous system. In extreme cases, iodine deficiency can lead to cretinism, a disorder that involves severely stunted physical and mental growth.

Iodine deficiency is a common world health problem. The most recognized form of deficiency is goiter. Additionally, across the globe iodine deficiency is thought to be the most common preventable cause of mental retardation. Early in the twentieth century, iodine deficiency was common in the US and Canada, but the addition of iodine to salt has improved public health. The addition of iodine to salt is required in Canada. In the US, iodized salt is not required, but it is widely available. Researchers estimate that iodized salt is used regularly by about half the US population.

Iodine is used to prevent and treat iodine deficiency and its consequences, including goiter and some thyroid disorders. It is also used for treating a skin disease caused by a fungus (cutaneous sporotrichosis); treating fibrocystic breast disease and breast pain (mastalgia); weight loss; preventing breast cancer, eye disease, diabetes, and heart disease and stroke; and as an expectorant. Iodine is also used for serious bacterial diseases called anthrax and syphilis.

Iodine is also used to for radiation emergencies, to protect the thyroid gland against radioactive iodides. Potassium iodide tablets for use in a radiation emergency are available as FDA-approved products (ThyroShield, Iosat) and on the Internet as food supplements. Potassium iodide should only be used in a radiation emergency, not in advance of an emergency to prevent sickness.

Iodine is applied to the skin for skin inflammation (dermatitis) and other skin disorders such as eczema and psoriasis, to kill germs and heal wounds, to prevent soreness inside the mouth or along the digestive tract (mucositis), and treat diabetic and other external ulcers. Iodine is also applied inside the mouth to treat gum disease (periodontitis) and reduce bleeding after the removal of a tooth. Iodine can also be used as a throat rinse to reduce symptoms of pneumonia.

Iodine is used in the eyes to reduce swelling in infants and to prevent vision loss in patients with ulcers of the cornea.

Iodine is used in the vagina to prevent post-Cesarean swelling of the lining of the uterus.

Iodine is injected into a portion of the pelvis to treat a condition called chyluria.

Iodine is also used for water purification.

How does it work?

Iodine reduces thyroid hormone and can kill fungus, bacteria, and other microorganisms such as amoebas. A specific kind of iodine called potassium iodide is also used to prevent thyroid damage after a radioactive accident.

Traditionally used for

Iodine deficiency.
Radiation exposure.
Thyroid conditions.
Leg ulcers.
Conjunctivitis (pinkeye).
Foot ulcers in diabetes.
Inflammation of the uterus (endometritis).
Painful fibrous breast tissue (fibrocystic breast disease).
Breast pain (mastalgia).
Soreness and swelling inside the mouth.
Gum infection (periodontitis).
Wound healing.



By Mouth:

For iodine deficiency: Consumption of iodized salt is recommended in most cases. For most people, iodized salt containing 20-40 mg of iodine per kilogram of salt is recommended. If salt consumption is less than 10 grams per person per day, the amount of iodine in salt may need to be higher.

In pregnant and lactating women, iodine supplements providing 250 mcg of iodine daily or a single annual dose of 400 mg of iodized oil are recommended.

For radiation emergencies: Potassium iodide (KI) should be taken just prior to, or as soon as possible after, exposure. Radiation is most harmful to pregnant or breastfeeding women and children, so KI is dosed according to amount of radiation exposure and age. Radiation exposure is measured in centigrays (cGy). For infants, babies, children, adolescents, and pregnant or breastfeeding women, KI is given if radiation exposure is 5 centigrays (cGy) or more.

For birth through 1 month, the dose is 16 mg of KI.
For babies and children over 1 month through 3 years, 32 mg.
For children 3 to 12 years, 65 mg.
For adolescents 12 through 18 years, 65 mg or 120 mg if the adolescent is approaching adult size.
For pregnant or breastfeeding women, 120 mg.
For adults 18 to 40 years with exposure to 10 cGy or more, 130 mg of KI is given.
For adults over 40 years with exposure to 500 cGy or more, 130 mg of KI is given.

For thyroid conditions:

For thyroid storm: Five drops of a saturated solution of potassium iodine every 6 hours is recommended.
For reducing the size of thyroid nodules: Iodized salt 150-200 mcg daily in addition to thyroxine 1.5 mcg per kg daily after surgery for benign nodular thyroid disease, or 50-100 mcg/day based on needs, for up to 12 months.

For painful fibrous breast tissue (fibrocystic breast disease): Molecular iodine 70-90 mcg/kg for 4-18 months.

For breast pain (mastalgia): Iodine 3000-6000 mcg daily for 5 months.

Applied on the Skin:

For venous leg ulcers: Topical application of cadexomer iodine to venous leg ulcers for 4-6 weeks. Also, solutions containing 10% povidone-iodine, ointment containing 10% povidone-iodine, and dry powder spray containing 2.5% povidone-iodine have been used in combination with compression therapy.

For diabetic foot ulcers: Topical iodine 0.9% ointment for 12 weeks.

For mouth sores (oral mucositis): 100 mL of a mouth rinse containing povidone-iodine solution used as a rinse for 3 minutes four times daily starting at the beginning of radiotherapy and continuing until one week after radiation is completed.

For gum inflammation (periodontitis): A rinse with 0.1% to 10% povidone-iodine used during scaling and root planing.

For surgery: Spray containing iodine in the form of povidone-iodine has been applied before and after wound closure. Also, solution containing 0.35% to 10% povidone-iodine has been applied for one to three minutes before or after wound closure.

Swelling of the uterine lining (endometritis): A vaginal wash containing iodine in the form of povidone-iodine 1% to 10% has been used immediately before Cesarean delivery.


By Mouth:

For iodine deficiency: Consumption of iodized salt is recommended in most cases. For most people, iodized salt containing 20-40 mg of iodine per kilogram of salt is recommended. If salt consumption is less than 10 grams per person per day, the amount of iodine in salt may need to be higher.

In children aged 7 months to 2 years, iodine supplementation may be necessary if iodized salt is not available. In those cases, supplements providing 90 mcg of iodine daily or a single annual dose of 200 mg of iodized oil is recommended.

Possible Side Effects

Iodine is SAFE for most people when taken by mouth at recommended amounts or when applied to the skin appropriately using approved products.

Iodine can cause side effects in some people. Common side effects include nausea and stomach pain, runny nose, headache, metallic taste, and diarrhea.

In sensitive people, iodine can cause side effects including swelling of the lips and face (angioedema), severe bleeding and bruising, fever, joint pain, lymph node enlargement, hives, and death. However, such sensitivity is very rare.

Large amounts or long-term use of iodine are POSSIBLY UNSAFE. Adults should avoid prolonged use of doses higher than 1100 mcg per day (the upper tolerable limit, UL) without proper medical supervision. In children, doses should not exceed 200 mcg per day for children 1 to 3 years old, 300 mcg per day for children 4 to 8 years old, 600 mcg per day for children 9 to 13 years old, and 900 mcg per day for adolescents. These are the upper tolerable limits (UL).

In both children and adults, there is concern that higher intake can increase the risk of side effects such as thyroid problems. Iodine in larger amounts can cause metallic taste, soreness of teeth and gums, burning in mouth and throat, increased saliva, throat inflammation, stomach upset, diarrhea, wasting, depression, skin problems, and many other side effects.

When iodine is used directly on the skin, it can cause skin irritation, stains, allergic reactions, and other side effects. Be careful not to bandage or tightly cover areas that have been treated with iodine to avoid iodine burn.

Special Precautions & Warnings

Pregnancy and breast-feeding: Iodine needs increase during pregnancy. Iodine is SAFE when taken by mouth in recommended amounts or when applied to the skin appropriately using an approved product (2% solution). Iodine is POSSIBLY UNSAFE when taken by mouth in high doses. Do not take more than 1100 mcg of iodine per day if you are over 18 years old; do not take more than 900 mcg of iodine per day if you are 14 to 18 years old. Higher intake has been shown to cause thyroid problems in the newborn in some cases.

Autoimmune thyroid disease: People with autoimmune thyroid disease may be especially sensitive to the harmful side effects of iodine.

A type of rash called dermatitis herpetiformis: Taking iodine can cause worsening of this rash.

Thyroid disorders, such as too little thyroid function (hypothyroidism), an enlarged thyroid gland (goiter), or a thyroid tumor: Prolonged use or high doses of iodine might make these conditions worse.

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